BARKER, DOUGLAS,ATNIKOV, KATRIN,ZHANG, YILAN,FROST, STEPHEN
申请号:
CACA2011/050330
公开号:
WO2011/150517A3
申请日:
2011.06.01
申请国别(地区):
WO
年份:
2012
代理人:
摘要:
The present invention relates to the field of the diagnosis of large intestine/colon diseases. More particularly, the present invention provides a method for differential diagnosis of colorectal cancer from a non-malignant disease of the large intestine/colon, and from a healthy large intestine/colon. The invention also relates to treatment of colorectal cancer. The peptide fragment, consisting of amino acids 62 to 110 of human Xyxin, was found to be significantly down regulated in serum samples obtained from colorectal cancer populations, as compared to serum samples obtained from healthy control populations and benign disease populations.La présente invention se rapporte au domaine du diagnostic des maladies du gros intestin ou du côlon. Elle concerne plus particulièrement un procédé de diagnostic différentiel du cancer colorectal à partir dune maladie non maligne du gros intestin ou du colon, et à partir dun gros intestin ou dun côlon sain. Linvention concerne en outre le traitement du cancer colorectal.