KIM, Yong Il,IM, Ho Taek,CHO, Hyuk Jun,YOON, Youngsu,PARK, Jae Hyun,WOO, Jong Soo
申请号：
PH12017501986
公开号：
PH12017501986A1
申请日:
2017.10.27
申请国别(地区):
PH
年份:
2018
代理人:
摘要：
Disclosed are a pharmaceutical composition for preventing or treating a cardiovascular disorder comprising amlodipine, rosuvastatin and losartan, and a pharmaceutical complex formulation comprising a first mixture part containing amlodipine and rosuvastatin and a second mixture part containing losartan. The composition and complex formulation comprise rosuvastatin having a particle size (D90) of 50 mm or less, and exhibit excellent dissolution rate, bioavailability, stability and content uniformity, and thus can be useful in pharmaceutical industries.
