Targeting of Ligand Binding Sites in CLFA

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专利权人:

发明人:

Vannakambadi K. Ganesh,Magnus Hook

申请号：

US15773372

公开号：

US20180369355A1

申请日:

2016.11.04

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody fragment or a composition that specifically binds to a portion of ClfA with the sequence of SEQ ID No: 15, SEQ ID NO: 16, SEQ ID NO: 17, and SEQ ID NO: 18.

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