PEREZ GARCIA, JUAN BAUTISTA,CARRERA CARRERA, FRANCESC,GARCIA MARTIN, DIGNA JOSE,BOIX BERNARDINI, MARIA CARMEN
申请号：
CA2754804
公开号：
CA2754804C
申请日:
2010.03.11
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention is directed to water-soluble pharmaceuticallyacceptable,crystalline addition salts of (i) an amine containing one or more hydroxyland/or carboxylicgroups with (ii) amino nicotinic acid derivatives of formula (I)wherein Ra, Rb, Rc and Rd independently represent groups selected fromhydrogen atoms,halogen atoms, C1-4 alkyl groups which may be optionally substituted by 1, 2or 3 substituentsselected from halogen atoms and hydroxy groups, and C1-4 alkoxy groups whichmay beoptionally substituted by 1, 2 or 3 substituents selected from halogen atomsand hydroxygroups, and pharmaceutically acceptable solvates thereof.see above formula
