CHUNTHARAPAI, ANAN,KIM, JIN K.,PRESTA, LEONARD G.,STEWART, TIMOTHY
申请号:
DK09002404
公开号:
DK2065467T5
申请日:
2002.01.29
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The present invention relates generally to the generation and characterization of neutralizing anti-IFN-± monoclonal antibodies with broad reactivity against various IFN-± subtypes. The invention further relates to the use of such anti-IFN-± antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-±, in particular, autoimmune disorders such as insulin-dependant diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).