ARIZONA BOARD OF REGENTS; A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
发明人:
SIERKS, Michael,KASTURIRANGAN, Srinath
申请号：
USUS2011/057887
公开号：
WO2012/058308A2
申请日:
2011.10.26
申请国别(地区):
WO
年份:
2012
代理人:
摘要：
The invention relates to antibodies, antibody fragments and binding agents that specifically recognizes oligomeric Aβ that is resistant to denaturation by SDS but does not bind monomeric, fibrillar or other oligomeric forms of Aβ that are generated in vitro.La présente invention concerne des anticorps, des fragments danticorps et des agents de liaison reconnaissant spécifiquement la beta-amyloïde (Aβ) oligomérique qui resiste à la dénaturation par SDS, mais ne se lie pas aux formes monomériques, fibrillaires, etc., de Aβ qui sont générées in vitro..
