CARLOS OLIANI,GUIDO VANDONI,ADRIANO P. COELHO,HENY C. ZANIBONI
申请号：
BR0302017
公开号：
BR0302017B1
申请日:
2003.06.02
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
The present invention describes the use of pharmaceutical compounds in pharmaceutical compositions for sublingual administration, including as active ingredient thereof, an agonist of the central receptor of benzodiazepinics chosen among diazepam, lorazepam, bromazepam, triazolam, alprazolam, flunitrazepam, nitrazepam and midazolam maleate, in a mixture with a pharmaceutical excipient consisting of, at least, 70% of the weight of the final formulation containing 40-45% by weight of lactose, 15-27% by weight of sorbitol and 12-16% by weight of cellulose.
