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Fgf receptor-activating n-acyl octasaccharides, preparation thereof, and therapeutic use thereof
专利权人:
SANOFI
发明人:
LASSALLE GILBERT,DUCHAUSSOY PHILIPPE,HERBERT CORENTIN,FONS PIERRE,DRIGUEZ PIERRE ALEXANDRE
申请号:
NZ59817410
公开号:
NZ598174A
申请日:
2010.08.12
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
598174 Disclose herein are N-acyl octasaccharide compounds of formula (I), wherein the variables are defined in the specification, in the acid form or in the form of any pharmaceutically acceptable salt thereof. These compounds are useful in the treatment of pathologies requiring activation of the FGF receptors or angiogenesis activation and post-ischaemic revascularisation, such as ischemia or arterial ischemia of the lower limbs and Parkinson&rsquos disease, Alzheimer&rsquos disease, prion disease or neuronal degeneration in alcoholics. Additionally disclosed are protected disaccharide units as intermediates in the synthesis of said octasaccharide compounds.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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