COMPOSITION COMPRENANT DE L'ACÉTATE D'ACIDE OLÉANOLIQUE EN TANT QUE PRINCIPE ACTIF POUR PRÉVENIR, ATTÉNUER OU TRAITER UNE TOXICITÉ RÉNALE INDUITE PAR UN MÉDICAMENT
Korea Research Institute of Bioscience and Biotechnology
发明人:
申请号：
EP17858748.1
公开号：
EP3524239A1
申请日:
2017.09.29
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention relates to a composition for preventing, improving or treating drug-induced nephrotoxicity, the composition comprising oleanolic acid acetate as an active ingredient. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating drug-induced nephrotoxicity comprising oleanolic acid acetate or a pharmaceutically acceptable salt thereof as an active ingredient, a health functional food for preventing or improving drug-induced nephrotoxicity comprising the active ingredients, and an anticancer adjuvant comprising the active ingredients. The oleanolic acid acetate of the present invention is derived from a natural product and has no side effects and no cytotoxicity and has excellent effects of preventing, improving and treating nephrotoxicity caused by a drug, particularly a platinum-based anticancer drug, so that it can be utilized as a pharmaceutical composition, a health functional food, and a cancer adjuvant thereof.
