A device includes a digit probe, a plurality of optical elements, a processor, and a communication module. The digit probe has an interior surface and has an exterior surface. The interior surface is configured to engage a digit and the exterior surface is configured to engage a tissue site associated with the digit. The plurality of optical elements is coupled to at least one of the interior surface and the exterior surface, The plurality of optical elements includes at least one emitter and includes at least one detector. The processor is coupled to the plurality of optical elements. The processor is configured to generate a measure of arterial oxygenation corresponding to the digit and configured to generate a measure of regional oxygenation corresponding to the tissue site. The communication module is coupled to the processor. The communication module is configured to communicate the measure of arterial oxygenation and regional oxygenation with a remote device.