Andreas Kling;Charles W. Hutchins;Francisco-Xavier Garcia-Ladona;Udo Lange;Wilhelm Amberg;Astrid Netz;Michael Ochse;Andrea Hager-Wernet
发明人:
Astrid Netz,Wilhelm Amberg,Udo Lange,Michael Ochse,Charles W. Hutchins,Francisco-Xavier Garcia-Ladona,Wolfgang Wernet,Andreas Kling
申请号:
US13021336
公开号:
US08481576B2
申请日:
2011.02.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to guanidine compounds of the general formula Icorresponding enantiomeric, diastereomeric and/or tautomeric forms thereof as well as pharmaceutically acceptable salts thereof. The present compound further relates to the use of guanidine compounds as binding partners for 5-HT5 receptors for the treatment of diseases which are modulated by a 5-HT5 receptor activity, in particular for the treatment of neurodegenerative and neuropsychiatric disorders as well as the associated signs, symptoms and dysfunctions.