Deutsches Krebsforschungszentrum Stiftung des oeffentlichen Rechts;Universitaetsklinikum Heidelberg
发明人:
Ana Martin-Villalba,Susanne Kleber,Benedikt Wiestler,Peter G. Krammer,Christel Herold-Mende,Ignacio Sancho-Martinez
申请号：
US14700521
公开号：
US09850308B2
申请日:
2015.04.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue.
