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徐放性製剤
专利权人:
塩野義製薬株式会社
发明人:
水谷 直也,木村 豪,西野 友規子,佐久間 聡
申请号:
JP2015560026
公开号:
JP6443891B2
申请日:
2015.01.30
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
Provided is an extended release formulation which is capable of controlling dissolution of a drug and of enduring peristaltic movement of the gastrointestinal tract. Specifically, the present invention is: a solid formulation comprising a drug, croscarmellose sodium, alkali metal salt or alkoxide, and an alkali agent, the alkali metal salt being a sodium salt or potassium salt, and the alkali agent being a magnesium oxide or a solid formulation comprising a drug, croscarmellose sodium, alkali metal salt or alkoxide, and a water-soluble polymer or hydrophobic base, the alkali metal salt being a sodium salt or potassium salt. The present invention is thus capable of providing an extended release formulation that controls dissolution of a drug and endures peristaltic movement of the gastrointestinal tract.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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