BRUNCKO, MILAN,SONG, XIAOHONG,DING, HONG,TAO, ZHI-FU,KUNZER, AARON R.,ELMORE, STEVEN W.,PARK, CHEOL-MIN,MADAR, DAVID,WANG, XILU,SOUERS, ANDREW J.
申请号：
PL08745934
公开号：
PL2134685T3
申请日:
2008.04.16
申请国别(地区):
PL
年份:
2016
代理人:
摘要：
Compounds of Formula I wherein A1, B1, C1, D1, E1, F1 and L1 are as defined herein, which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mcl-1 protein, such as leukemia and lymphoma, are disclosed.
