The actual production of this compound or its pharmaceutically acceptable salt regulated cyclophosphate gloves ("GMPC") is generally suitable for the treatment and prevention of diseases related to disturbed GMPC balance. It also provides pharmaceutical synthesis including hockey compoundsA (1) or a salt acceptable on a drug. It also refers to procedures for the use of compounds or salts acceptable in drugs in the treatment and prevention of these diseases and in the preparation of drugs for this purpose. 1. Requirement 1: a formula compound (1)O includes: X is C (H) or N； each R1 is an independent halogenated, hydroxy, and hydrocarbyl c833183323；C₃₋₆ cycloalkyl or -O-C₁₋₃ alkyl；R² is: (a) C₁₋₆ alkyl,said C₁₋₆ alkyl of R² being unsubstituted or substituted with 1 to 6 residues independently selected from fluoro or -O-C₁₋₃ alkyl；(b) C2 ring,the C² ring being: (i) C₃₋₁₂ cycloalkyl；(ii) phenyl； (iii) a 5- or 6-membered monocyclic heteroaryl containing 1 to 2 heteroatoms selected from N, O, or S； or (iv) a 5- or 6-membered monocyclic heterocyclyl containing 1 to 2 heteroatoms selected from N, O, or S； the C² ring being unsubstituted or substituted with 1 to 3 residues independently selected from halo, cyano, C₁₋₃-alkyl,-O-C₁₋₃-alkyl or oxo； R⁴ is C₁₋₆ alkyl,CF o cicloalquilo CC 3 ring is: (a) phenyl； (b) monocyclic heteromorphism composed of 5 to 6 members, or bicyclic heteromorphism composed of 9 to 10 members, including 1 to 3 heteromorphic atoms selected from n or s； (c) monocyclic heteromorphism composed of 5 to 6 members, including 1 to 3 heteromorphic atoms selected from n or s； (d) cycloquilo c83231 and c83268326；2. Select each r74919 without considering halide, cyanogen and c83231 / 8323；-O-lessor c8321c83183323,Oxo or hydroxy； and: (a) link； (b) represents a formula group (2),wherein RY¹ and RY² are independently H, C₁₋₃ alkyl,hydroxyl, fluoro, C₁₋₃ hydroxyalkyl or amino； or alternatively RY¹ and RY²,together with the carbon atom to which they are attached the
