Manojkumar A. Puthenveedu,Daniel J. Shiwarski,Amynah Pradhan
申请号:
US14799276
公开号:
US20160008430A1
申请日:
2015.07.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Described herein is a method to induce surface trafficking of the delta-Opioid Receptor (DOR) and its applications, including, leveraging the antinociceptive potential of DOR agonists to treaty neurologic disorders and to be analgesics without the adverse consequences normally associated with chronic treatment by MOR agonists by inducing surface trafficking of the delta-Opioid Receptor (DOR) and screening compounds to identify additional targets for stimulated DOR delivery.