Cyclopentyl ammonium sulfite derivatives and their use as hepatitis B drugs, Hexabromodiphenyl replication inhibitors. It also referred to the process of producing these compounds, the pharmaceutical ingredients containing them, the use alone in the treatment of Hexabromodiphenyl or in combination with other inhibitors of Hexabromodiphenyl, and the intermediary use in preparation for Hexabromodiphenyl. The remaining formula (2) represents a single ring arile, consisting of 5 or 6 members, optionally including one or two heteroatoms,such as aryl which is optionally substituted with one or more substituents, each independently selected from the group consisting of C₁₋₃ alkyl,In particular, methyl, cyclopropyl-83238331-8324；-CN y hal geno el resto de f rmula (3) representa un arilo de 6 miembros que contiene opcionalmente un tomo de nitr geno X representa -CR R -Y represents, C₁₋₇ alkanediyl or C₂₋₇ alkenodiyl,each optionally substituted with one or more substituents each independently selected from the group consisting of C₁₋₄ alkyl,Z represents heteroatom, preferably NH or oxygen, preferably oxygen or simple bond； r7491；R74955,R758080 and r74966 were selected from the group consisting of hydrogen, halogen and chf83222, respectively；-Cf-832222-methyl-ch-83222； - cf-83323；-OCF8323,-CN, C₃₋₄ cycloalkyl and - (C₁₋₄ alkyl)；R¹ is hydrogen or C₁₋₁₀ alkyl optionally substituted with one or more substituents, each independently selected from the group consisting of -OH, fluoro and oxo； R² is selected from the group consisting of hydrogen； C₁₋₁₀ alkyl optionally substituted with one or more substituents, each independently selected from the group consisting of -OH, fluoro, methoxy, oxo and -C (= O) O (C₁₋₄ alkyl)；(Alquilo C) -R1. C83228331 asphalt；a. A saturated ring composed of 3-7 members, including one or more heteroatoms, each selected independently from the O, s and N groups； a single ring arilo, including one or two heteroatoms； wherein (tar c833183323-r8311811)；a. 3-7 s
