MONOCLONAL ANTIBODY CAPABLE OF BINDING TO SPECIFIC DISCONTINUOUS EPITOPE OCCURRING IN AD1 REGION OF HUMAN CYTOMEGALOVIRUS GB GLYCOPROTEIN, AND ANTIGEN-BINDING FRAGMENT THEREOF

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专利权人:

发明人:

TAKADA KENZO,KURINO RIKA,TORASHIMA TAKASHI

申请号：

IN7306/CHENP/2011

公开号：

IN2011CN07306A

申请日:

2011.10.10

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

The present invention provides a pharmaceutical composition for human cytomegalovirus HCMV causative of various disease states, the composition comprising a monoclonal antibody and an antigen-binding fragment thereof that specifically binds to the AD 1 region of glycoprotein gB and that has excellent neutralizing capacity. The present invention provides: a monoclonal antibody and an antigen-binding fragment thereof having an excellent neutralizing capacity and cell-to-cell infection blocking capacity and specifically binding to a discontinuous sequence occurring in the HCMV AD1 region a pharmaceutical composition comprising the antibody or the fragment thereof and the like.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/