LINZ, KLAUS,KOEGEL, BABETTE-YVONNE,SCHROEDER, WOLFGANG,CHRISTOPH, THOMAS,DE VRY, JEAN,FRIDERICHS, ELMAR
申请号:
CA2664702
公开号:
CA2664702C
申请日:
2007.09.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The invention relates to the use of compounds having an affinity for the µ opioid receptor of at least 100 nM (Ki human value) and an affinity for the ORL-1 receptor for producing a medicament for treating pain, the ratio between the ORL1/µ affinities defined as 1/[Ki(ORL1)/Ki(µ)] being between 0.1 and 30.