The Board of Trustees of the University of Illinois
发明人:
Martin D. Burke,Anuj Khandelwal,Jiabao Zhang,Anna SantaMaria
申请号:
US16563243
公开号:
US20200079811A1
申请日:
2019.09.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are derivatives of amphotericin B (AmB) characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising the AmB derivatives, therapeutic methods of using the AmB derivatives and methods of making the AmB derivatives.