PROBLEM TO BE SOLVED: To provide means for increasing follicular regulatory T-cell (Tfr cell) with high safety, for example, Tfr cell increasing agents administered to a subject in which follicular helper T cells (Tfh cell) in blood are excessively increased.SOLUTION: A lactic acid bacterium belonging to Lactobacillus, for example, Lactobacillus paracasei MCC1849 (NITE BP-01633) is contained as an active ingredient in medicines, foods and drinks, food and drink compositions, and feed and the like which are used for increasing Tfr cells.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】安全性の高い、濾胞性制御性T細胞(Tfr細胞)を増加させる手段、例えば、血液中の濾胞性ヘルパーT細胞(Tfh細胞)が過剰に増加した対象に投与されるTfr細胞増加剤の提供。【解決手段】ラクトバチルス属に属する乳酸菌、例えばラクトバチルス・パラカゼイMCC1849(NITE BP-01633)を、Tfr細胞増加用に用いられる医薬、飲食品、飲食品組成物又は飼料等の有効成分とする。【選択図】なし
