Substituted furo[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents

• 收藏
• 分享

专利权人:

发明人:

Aleem Gangjee

申请号：

US14971121

公开号：

US09777012B2

申请日:

2015.12.16

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Compounds of Formula I:and compounds of Formula II:are provided. Pharmaceutical compositions comprising either the compound of Formula I or Formula II are disclosed. Methods of treating patients having cancer are provided by administering to the patient a therapeutically effective amount of one or more compounds having Formula I or Formula II to treat the patient. The compounds of Formula I or II are preferably conformationally restricted furo[2,3-d]pyrimidines having dual inhibition of microtubule assembly and receptor tyrosine kinases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/