Daniel T. Stinchcomb,Jill A. Livengood,Lazlo Varga
申请号：
US14209921
公开号：
US20140271715A1
申请日:
2014.03.13
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Embodiments herein relate to compositions of and methods for live attenuated alphaviruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated alphaviruses and compositions to reduce inactivation and/or degradation of the live, attenuated alphavirus. In other embodiments, the live, attenuated virus composition may be a vaccine composition. In yet other compositions, a live, attenuated alphavirus composition may include HEPES buffer. In other embodiments, the HEPES buffer may further include a carbohydrate and gelatin and/or a salt.
