University of Utah Research Foundation;Trustees of Boston University
发明人:
Jerome S. Brody,Avrum Spira,Adam Gustafson,Andrea Bild
申请号：
US14500475
公开号：
US20150232945A1
申请日:
2014.09.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides the identification of oncogenic pathways activated in cytologically normal airway cells of individuals having or at risk of having lung disease, as well as specific gene expression patterns (biomarkers) associated with pathway activation. These biomarkers and pathways may provide prognostic and/or diagnostic indicators in lung disease, e.g., lung cancer. Additionally, these pathways and biomarkers may provide therapeutic targets for the treatment of lung disease, as well as markers for the assessment of treatment efficacy.
