GeneDesign, Inc.;NOF Corporation;National University Corporation Chiba University
发明人:
Hideo Iba,Takeshi Haraguchi,Hirokazu Nankai,Hideaki Sato
申请号：
US16494743
公开号：
US20200032262A1
申请日:
2018.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided is a novel technique for treating cancer using structurally-reinforced S-TuD. Provided are: a composition for the prevention or treatment of tumors, said composition comprising an miRNA inhibitory complex including RNA of analog thereof； and a method for preventing or treating tumors using said composition. The miRNA inhibitory complex preferably includes at least one double-stranded structure and an miRNA-binding sequence. Two strands of the miRNA binding sequence preferably bind individually to two strands on at least one end of the double-stranded structure. According to some of the aspects of the present invention, there is provided a delivery system for delivering such an miRNA inhibitory complex.
