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SMALL MOLECULE MODULATORS OF THE COLD AND MENTHOL RECEPTOR TRPM8
专利权人:
Michael Krohn
发明人:
Michael Krohn,Holger Zinke
申请号:
US14003762
公开号:
US20130345300A1
申请日:
2012.03.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to the use of compounds which are capable of producing a cooling sensation when they are brought into contact with the human body. In particular, the present invention relates to the use of compounds modulating TRPM8, and optionally to the use of compounds selectively exhibiting agonist activity at the TRPM8 channel. Such compounds have applications in many fields, particularly in oral and personal hygiene products and foodstuffs, but also in pharmaceutical composition products, cosmetics, textile products and packaging products. The present invention further relates to products containing such compounds and to the medical use of such compounds.
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