UNIVERSITY OF MARYLAND EASTERN SHORE;UNIVERSITY OF MARYLANDBALTIMORE OFFICE OF TECHNOLOGY TRANSFER;UNIVERSITY OF MARYLAND BALTIMORE;THOMAS JEFFERSON UNIVERSITY
发明人:
UNIVERSITY OF MARYLANDBALTIMORE OFFICE OF TECHNOLOGY TRANSFER
申请号:
IL24082015
公开号:
IL240820D0
申请日:
2015.08.25
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant. The compounds are potential agents for the treatment of all forms of prostate cancer and other diseases that depend on functional AR.