An oral care composition comprising a compound, wherein the compound comprises: (a) a cation; and (b) an anion, wherein the compound has two or more of (i) an atomic polarizability of from 20 to 60, (ii) a Kier flexibility index of from 2 to 20 and (iii) a molar refractivity of from 3 to 10 is provided.本發明係提供含化合物之口腔護理組成物,其中,該化合物包含:(a)陽離子;及(b)陰離子,其中該化合物具有下列之二種以上:(i)由20至60之原子極化係數,(ii)由2至20之基爾撓性指數(Kier flexibility index),及(iii)由3至10之莫耳折射係數。