Susan M. Freier,Brett P. Monia,Hong Zhang,Jeffrey R. Crosby,Chenguang Zhao
申请号：
US13384327
公开号：
US20120214862A1
申请日:
2010.07.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are antisense compounds and methods for decreasing Factor 7 and treating or preventing thromboembolic complications in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 7 include thrombosis, embolism, and thromboembolism, such as, deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke. Antisense compounds targeting Factor 7 can also be used as a prophylactic treatment to prevent individuals at risk for thrombosis and embolism.
