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Altering Cancer Cellular Functions through Proton Mopping
专利权人:
Michael Theodore Lytinas
发明人:
Michael Theodore Lytinas
申请号:
US14479619
公开号:
US20150072944A1
申请日:
2014.09.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Proton mopping is a new anti-cancer therapeutic approach that disrupts cancers immunologic balance. It results in the alteration of the pHi/pHe ratio (intracellular-extracellular) of the cancer cell, leading cancer to either normalcy or apoptosis. This technology deploys a chemical compound that has two parts, a glucose part to guide the molecule to the cancer site and a proton neutralizer to mop up the protons. Proof of the validity of this therapeutic approach came after using an existing chemical compound 2-[2(2-Aminoethoxy)ethoxy]ethyl a-D-mannopyranoside, C12H25NO8, which has the above mentioned properties. This compound is of the class of functionalized PEGylated glycosides, which are ligands for conjugation to biological molecules.
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中国工程科技知识中心
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