NAEYE THIERRY,EINERHAND ALEXANDRA,LOPEZ MICHEL,POTTER SUSAN M,REMAUD SIMEON MAGALI,MONSAN PIERRE FREDERIC EMMANUEL
申请号:
IN8402/DELNP/2011
公开号:
IN2011DN08402A
申请日:
2011.10.31
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Compositions for improving the health of a subject comprise alpha-(l,2)-branched alpha-(l,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(l,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(l,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(l,2)-osidic side chains onto the alpha-(l,6) oligodextrans.