Sei Ryang Oh;Kyung Seop Ahn;Ok-Kyoung Kwon;Hyeong Kyu Lee;Joongku Lee;Hyouk Joung;Mee-Young Lee;Hwa-Young Son;Kyoung-youl Lee;Sang Woo Lee;Hang Jin;Wan Yi Li
发明人:
Sei Ryang Oh,Kyung Seop Ahn,Ok-Kyoung Kwon,Hyeong Kyu Lee,Joongku Lee,Hyouk Joung,Mee-Young Lee,Hwa-Young Son,Kyoung-youl Lee,Sang Woo Lee,Hang Jin,Wan Yi Li
申请号：
US13985533
公开号：
US08883226B2
申请日:
2012.02.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-α in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.
