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Boronates AS ARGINSASEINHIBITORER
专利权人:
MARS; INCORPORATED
发明人:
VAN ZANDT, MICHAEL,JAGDMANN, JR., GUNNAR ERIK
申请号:
DK11779904
公开号:
DK2632927T3
申请日:
2011.10.19
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
Compounds according to Formula I are potent inhibitors of Arginase I and II activity: where R 1 , R 2 , R 3 , R 4 , D, W, X, Y, and Z are defined in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use in treating or preventing a disease or a condition associated with arginase activity.
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