Problem to be solved: to provide an injectable nano particle active substance pharmaceutical which does not substantially contain flake like particles.(a) nanoparticle injectable composition comprising (a) an active substance having an effective average particle size of less than about 2000 nm, (b) at least one surface stabilizer adsorbed on the surface of said active material, and (c) a flake like agglomeration inhibitor.Diagram【課題】フレーク状粒子を実質的に含有しない、注射可能なナノ粒子活性物質製剤の提供。【解決手段】(a)約2000nm未満の有効平均粒径を有する活性物質、(b)該活性物質の表面上に吸着される少なくとも1つの表面安定剤、および(c)フレーク状凝集軽減剤を含むナノ粒子注射可能組成物。【選択図】図1