The present invention relates to compositions and methods for preventing andtreating osteochondrosis by administration of supplemental boron containingcompounds to animals and humans. The supplemental boron containing compoundsare provided in animal feed compositions or as supplements for animal feed.Also provided by this invention are animal feed compositions that aresupplemented with boron containing compounds and which have reduced phosphoruscontent. The invention also provides a method for treating or preventingosteochondrosis in animals or humans by the administration of supplementalboron containing compounds. The invention also provides a method fordecreasing the amount of phosphorus excreted by an animal, a method ofincreasing the efficiency of absorption of phosphorus by an animal, a methodof reducing environmental phosphorus pollution by administering supplementalboron to the animal. The invention also provides a method of reducing pre-weaning mortality in an animal by feeding pregnant, nursing or lactatinganimals by administering supplemental boron containing compounds.