GENERAL ELECTRIC COMPANY;SUNNYBROOK RESEARCH INSTITUTE
发明人:
LAU, ANGUS ZOEN,CHEN, ALBERT PO-FU,CUNNINGHAM, CHARLES H.
申请号：
CA2848108
公开号：
CA2848108A1
申请日:
2014.04.03
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Disclosed embodiments for assessing brown adipose tissue use imaging ofmetaboliccontrast agents. For example, activated brown adipose tissue may be assessedbyevaluating a difference in production of the hyperpolarized 13C metaboliccontrast agentfrom a pre-polarized 13C metabolic contrast agent precursor before and afterexposure ofthe subject to an activating event or agent. In one embodiment, the subject isgiven adose of norepinephrine, and the production of the hyperpolarized 13C metaboliccontrastagent before and after the dose is assessed.
