LIFE SCIENCE INSTITUTE, INC.;NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
发明人:
SATO, YOSHIAKI,SUZUKI, TOSHIHIKO,SHIMIZU, SHINOBU,MIZUNO, MASAAKI,HAYAKAWA, MASAHIRO,DEZAWA, MARI
申请号:
CA3024518
公开号:
CA3024518A1
申请日:
2017.05.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention addresses the problem of providing a novel use of pluripotent stem cells (Muse cells) for medical purposes in regenerative medicine. The present invention provides a cell preparation and a pharmaceutical composition both for ameliorating and treating perinatal brain damage including learning disability and motor disability, each of the cell preparation and the pharmaceutical composition containing SSEA-3-positive pluripotent stem cells separated from a mesenchymal tissue collected from a living body or cultured mesenchymal cells. The cell preparation according to the present invention relies on a mechanism that Muse cells are administered to a subject having the above-mentioned damage to cause the engraftment of the Muse cells in a damaged brain tissue, thereby ameliorating and treating the damage.