Described is a medical adapter assembly comprising an end including a neuraxial fitting that is not directly connectable to a standard luer fitting, an opposing end including a standard luer fitting connectable to a standard luer fitting of an intravenous medical device, and a check valve that allows fluid flow from the end with the standard luer fitting to the end with the neuraxial fitting, but prevents fluid flow from the end with the neuraxial fitting to the end with the standard luer fitting. Methods of using the medical adapter assembly and kits containing the medical adapter assembly are also described.