The present invention relates to a Lactuca sativa seed designated 41-177 RZ, which exhibits a combination of traits including resistance against downy mildew (Bremia lactucae) races Bl:1-28 and Ca-I to Ca-VIII, currant-lettuce aphid (Nasonovia ribisnigri) biotype Nr:0, lettuce mosaic virus (LMV), and corky root rot (Sphingomonas suberifaciens), as well as solid main veins and narrow base leaves. The present invention also relates to a Lactuca sativa plant produced by growing the 41-177 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 41-177 RZ.
