The Board of Trustees of the Leland Stanford Junior University
发明人:
Albert C. Koong,Douglas E. Feldman
申请号:
US13764200
公开号:
US20130150399A1
申请日:
2013.02.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds that are inhibitors of the unfolded protein response and endonuclease IRE1 are provided, together with compositions comprising such compounds, and methods for their use in the treatment of various disorders, such as cancer, autoimmune disorders, and diabetes. Also provided are packaged pharmaceuticals comprising these compositions. The compositions may be administered in combination with another therapeutic agent.