GURNETT-BANDER ANNE,ARRECUBIETA CARLOS,LOWY ISRAEL
申请号:
NZ62894313
公开号:
NZ628943A
申请日:
2013.03.01
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Discloses an isolated antibody that specifically binds to Clostridium difficile toxin A comprising the three heavy chain complementarity determining regions (HCDR1, HCDR2 and HCDR3) contained within a heavy chain variable region (HCVR) amino acid sequence of SEQ ID NO: 146; and the three light chain complementarity determining regions (LCDR1, LCDR2 and LCDR3) contained within a light chain variable region (LCVR) amino acid sequence of SEQ ID NO: 154, wherein the sequences are as defined in the complete specification. Further discloses pharmaceutical compositions and uses in treating patients suffering from Clostridium difficile related conditions.