The invention relates to an appliance for disinfecting the hands of a user, said appliance including: a disinfection chamber (1), at least one opening (10) through which the user inserts his or her hands (M) in the disinfection chamber separators (4) placed in the disinfection chamber (1) such that the fingers are separated when the user inserts his or her hands in said chamber, characterised in that the disinfection chamber (1) is provided with a device for spraying a disinfectant product in said chamber and a device for blowing air into said chamber, said two devices operating at the same time, and in that the spraying device consists of injectors (11a, 11b, 12a, 12b) suitable for scattering a disinfectant product into the blown air stream, the scattering of the disinfectant product being carried out in a spatial sector defined by a vertical plane and an inclined plane of 1° to 90°, preferably 45° to 90°, relative to the axis of said air stream.