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Identification and selection of stem cells involved in differentiating into specific types to obtain uniform stem cell populations
专利权人:
ダボス;アーオー-フォルシュングスインスティチュート;アーオー-フォルシュングスインスティチュート ダボス
发明人:
アリニ,マウロ,シュトッダート,マーティン,アリニ,マウロ,シュトッダート,マーティン
申请号:
JP2009523122
公开号:
JP5286265B2
申请日:
2006.08.11
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
The stem cell (1) includes a cellular DNA (2) comprising a plurality of sequences coding different genes and promoters allowing DNA-protein-interactions, at least one protein molecule (3) generated by means of a specific stimulus (12) and at least one DNA-molecule (6) artificially introduced into the stem cell (1). The artificially introduced DNA-molecule (6) comprises at least one binding site sequence (30) being apt to interact with the protein molecule (3), at least one DNA-sequence (40) coding an indicator molecule (5) and at least one minimal promoter sequence (50), allowing the gene expression of said indicator molecule (5), whereby the stem cell further includes at least one indicator molecule (5) having properties allowing its identification and is produced by synthesis of the DNA-sequence (40) coding an indicator molecule (5) of the artificially introduced DNA-molecule (6).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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