PROBLEM TO BE SOLVED: To provide a sepsis therapeutic or prophylactic nutritional composition containing amino acid that is effective in septic therapy or prevention, with less concern over side effects compared with existing drugs, such as an antibacterial drug, without causing drug resistance, and further with low cost.SOLUTION: The invention provides a sepsis therapeutic or prophylactic nutritional composition characterized by containing three kinds of amino acids of lysine, histidine, and tryptophan, as well as a pulmonary or hepatic dysfunction therapeutic or prophylactic nutritional composition characterized by containing three kinds of amino acids of lysine, histidine, and tryptophan.SELECTED DRAWING: Figure 2COPYRIGHT: (C)2016,JPO&INPIT【課題】 敗血症の治療や予防に有効で、抗菌薬などの既存の薬物に比べて、副作用の心配が少なく、薬剤耐性が生じることなく、しかもコストが安い、アミノ酸含有の敗血症治療又は予防用栄養組成物を提供する。【解決手段】 リジン、ヒスチジン及びトリプトファンの3種のアミノ酸を含有ることを特徴とする敗血症治療又は予防用栄養組成物。リジン、ヒスチジン及びトリプトファンの3種のアミノ酸を含有することを特徴とする肺または肝臓障害治療又は予防用栄養組成物。【選択図】 図2