FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITAGE (IDIBELL)
发明人:
Josep M. ARAN PERRAMON,Luis Antonio RUIZ AVILA,Jordi ORTIZ SAGRISTA,Nuria LLUCH LAFUENTE
申请号：
US16603427
公开号：
US20200148731A1
申请日:
2018.04.05
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to compounds for use in the prevention and/or treatment of immunological diseases, particularly rheumatoid arthritis systemic lupus erythematosus and lupus nephritis, characterized by the subcutaneous administration of isoforms of C4BP lacking the beta chain or polypeptides comprising the CCP6 region of the alpha chain of C4BP no more than once a week or at a dose ranging from 0.24 mg/m2 to 9.99 mg/m2. The invention also relates to pharmaceutical compositions comprising from 0.45 mg to 18.90 mg of said compounds for the prevention and/or treatment of said diseases.
