Disclosed is a composition for reducing the exudation of the serum proteins.More specifically, the composition of the present invention relates to acomposition capable of improving conditions such as atopic dermatitis, atopiceczema, skin pruritus, atopic nasitis, atopic erythema or erythroderma,contact dermatitis, asthma, chronic obstructive pulmonary disease, etc. byreducing the exudation of the serum proteins in skin and mucosa.