A method for 3-D cephalometric analysis of a patient, executed at least in part on a computer processor, displays reconstructed volume image data from a computed tomographic scan of a patients head from at least a first 2-D view and accepts an operator instruction that positions and displays at least one reference mark on the at least the first displayed 2-D view. One or more dentition elements within the mouth of the patient are segmented and one or more cephalometric parameters computed for the patient according to the at least one reference mark and the one or more segmented dentition elements. One or more results generated from analysis of the one or more computed cephalometric parameters are displayed.