Matthew Frederick LeFebvre,Yasuko Hatta,Pamuk Bilsel,Michael J. Moser
申请号：
US15125763
公开号：
US09757446B2
申请日:
2015.03.13
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
