The present invention relates to crystalline forms of dihydropyrimidine derivatives, and pharmaceutical compositions comprising the crystalline forms disclosed herein, which may be used for preventing, managing, treating or lessening the severity of a viral disease in a patient, especially hepatitis B infection or a disease caused by hepatitis B infection.本發明涉及二氫嘧啶衍生物的晶型,並提供包含這些晶型或其互變異構體或其組合或使用這些化合物製備的藥物組合物,在製備用於防護、處理、治療或減輕患者病毒性疾病的藥物中的用途,特別是乙型肝炎感染或乙型肝炎感染所引起的疾病。