Disclosed is a transdermal drug delivery device that comprises a. an active ingredient (AI) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component b. a release liner adjacent the skin contacting surface of the AI layer, which release liner is impermeable to the volatile component and the perimeter of which extends beyond the perimeter of the AI layer in all directions and c. an overlay comprising a first pressure sensitive adhesive (PSA) adjacent the non-skin contacting surface of the AI layer, the perimeter of which extends beyond the perimeter of the AI layer in all directions, wherein the AI layer is a matrix comprising a second PSA, and the volatile component is at least partly solubilized in said second PSA the solubility of the volatile component in the first PSA of the overlay is less than the solubility of said component in the second PSA of the AI layer the release liner and the first PSA of the overlay are in contact with and adhered to each other around the perimeter of the AI layer to form a seal.
